8-9 December 2017


Medical Center of the Johannes Gutenberg University Mainz
Provisional title: Generation of new interneurons by direct lineage reprogramming in the brain

Dr Benedikt Berninger is currently full professor of Physiological Chemistry at the University Medical Center of the University Mainz. Benedikt received his doctoral degree in 1996 at the Ludwig Maximilians University Munich for work on activity-dependent regulation of neurotrophin gene expression. He then joined the lab of Professor Mu-ming Poo as a postdoctoral fellow at the University of California San Diego to study fast actions of neurotrophins on synapses and growth cones. After a brief stay at the Karolinska Institute (Stockholm, Sweden), Benedikt returned to Munich and eventually obtained a position as senior lecturer at the Ludwig Maximilians University Munich. In 2012 he received a call to the Johannes Gutenberg University of Mainz. The work of his laboratory focuses on lineage progression of adult neural stem cells, the functional integration of adult-generated neurons into pre-existing circuits, and on direct conversion of brain-resident cells into induced neurons.


University of Michigan
Provisional title: Stem Cell Therapy in ALS: Where We Are Today.

Dr. Eva L. Feldman received her M.D. and Ph.D. degrees from the University of Michigan (U-M), completed a neurology residency at the Johns Hopkins Hospital and returned to U-M for a Neuromuscular fellowship. In addition to her clinical practice and position as the Russell N. DeJong Professor of Neurology at the U-M Medical School, Dr. Feldman is Director of the A. Alfred Taubman Medical Research Institute and Director of Research for the U-M ALS Clinic. She also runs her own 30-scientist laboratory, the Program for Neurology Research & Discovery, and is the principal investigator of two first-ever FDA approved human clinical trials of intraspinal stem cell implantation therapy for ALS.

National Expert Motor Neuron Diseases Center, University of Novara
Provisional title: “Stem cell strategies and cell products in motor neuron diseases

Letizia Mazzini is a neurologist, Director of the Tertiary ALS Center at the University of Novara The main scientific interests are in the field of basic and clinical research on motor neuron diseases. She cooperated as investigator in many multicenter therapeutic trials in ALS. Head of the first phase 1 study authorized by the Italian Institute of Health on clinical application of mesenchymal autologous stem cells in ALS and clinical coordinator of the phase 1 and phase II clinical studies on neural fetal stem cell transplantation in ALS. She has authored or co-authored 142 papers on peer-reviewed international journals, as well as books, edited books, e-books. She received more than 3323 citations, with h-index = 32 (Sources: ISI Web of Knowledge and Scopus). She acted as reviewer for several journals in the fields of ALS. Actually member of the Italian neurological society subgroup on MND and of the scientific advisory board of the Italian ALS Association.

Emory University, Atlanta
Provisional title: "Surgical Approaches to Motor Neuron Protection".

I have conducted basic, translational, and clinical neuroscience in six laboratories over a 16-year period prior to launching an independent laboratory in 2001. My research evolved from an interest in neuroplasticity applied to emotion, learning, and memory into a focus on repair of the nervous system for traumatic and degenerative disease. My laboratory focuses on the development of gene and cellular therapies for neurodegenerative and functional diseases of the nervous system. A variety of viral vectors are currently being tested in both neuronal cell cultures and in animal models of ALS and spinal muscular atrophy. In parallel, the Boulis laboratory focuses on the development of tissue-specific targeting strategies. These approaches are designed to deliver molecular therapeutics to an anatomically defined site of interest. Much of this effort has concentrated on motor neuron-specific gene delivery.

Professor of Neurology with Tenure and Frank M. Yatsu Chair in Neurology
McGovern Medical School at The University of Texas Medical School at Houston

Education (Degree)
1995 B.A. Harvard University
2000 M.D. Albert Einstein College of Medicine
2000-2001 Intern in Medicine, Beth Israel Deaconess Medical Center
2001-2003 Resident, Beth Israel Deaconess Medical Center and Children’s Hospital
2003-2004 Administrative Chief Resident, Beth Israel Deaconess Medical Center

Neurosurgery Department, UCSF, San Francisco
Provisional title: "Gene therapy for severe neurological condition caused by genetic mutation in children"

Professor Krzysztof Bankiewicz is a leader in gene therapy to the brain who has brought multiple AAV-based therapies to the clinic. He is the Kinetics Foundation Chair in Translational Research and tenured Professor in Residence of Neurological Surgery and Neurology at the University of California at San Francisco (UCSF). Prof. Bankiewicz is also Vice Chair for Research in the Department of Neurosurgery and Director of Interventional Neurology Center (INC) at UCSF and co-Director of INC at Brodno Hospital in Warsaw, Poland. Prof. Bankiewicz has both industry and academic experience, is an inventor on numerous patents and has published over 200 peer-reviewed research articles.

PhD, D.Sc, (Division of Neuroscience, School of Biological Sciences in Manchester)
Provisional title: "Astroglia in cognitive disorders: do human iPSCS-derived cells hold the key?"

Member of Academia Europaea (2003), Member of the German National Academy of Sciences Leopoldina (2013), Member of Real Academia Nacional de Farmacia of Spain (2012), member of The Dana Alliance for Brain Initiatives (2012). He joined the Division of Neuroscience, School of Biological Sciences in Manchester in September 1999, became a Professor of Neurophysiology in 2002 and served as Head of the said Division from 2002 to 2004. From 2007 to 2010 he was appointed as a visitor professor/Head of Department of Cellular and Molecular Neurophysiology at the Institute of Experimental Medicine, Academy of Sciences of Check Republic. Alexei also serves as a Research Professor of the Ikerbasque (Basque Research Council) in Bilbao, where, from 2012, he acts as Adjunct Scientific Director of the Achucarro Basque Center for Neuroscience; from 2011 he is as a Honorary Visitor Professor at Kyushu University, Fukuoka, Japan. Alexei is the editor-in-chief of Cell Calcium, Receiving Editor of Cell Death & Disease and member of editorial boards of many journals including Pflugers Archiv European Journal of Physiology, Glia, Purinergic Signalling, ASN Neuro &c.

The University of Warmia and Mazury in Olsztyn, Poland
USK Olsztyn, Poland

During study in Medical University in Warsaw working in research in Department of Physiology (prof. A. Trzebski, P. Szulczyk)  and in Department of Neurosurgery (prof. L. Stępień, J. Bidziński).  Graduated in 1980, specializing in neurosurgery and working in the Department of Neurosurgery as senior assistant and adjunct professor till 1992. He was trained in European Course in Neurosurgery –1988-1992. Doctor of Medical Sciences in 1988 and doctor of philosophy (habilitation) in 1994. Professor of Medicine – scientific title conferred by President of Republic – 2006. 

Division of Stem Cell Biology and Histology, Tohoku University Graduate School of Medicine

Tissue stem cells are present in every adult tissue and generally exist in a dormant state. When a tissue undergoes stress or is in a critical state, the inherent stem cells are activated by an as yet-to-be-defined signal to re-enter the cell cycle for self-renewal and differentiation into cells that aid in reconstruction of that tissue. In this manner, tissue stem cells participate in maintenance of homeostasis at the cell- or tissue-level. In our research, we seek to clarify how the signals aroused from neighboring cells or from other tissues regulate the maintenance, proliferation and differentiation of tissue stem cells, and how the tissue stem cell network is related to the maintenance of vital tissue functions. Our ultimate goal is to develop stem cell biology from a new perspective. By identifying multi-potential stem cells contained in the bone marrow stromal cell population that can be experimentally manipulated to differentiate into cells that have the potential to trans-differentiate and contribute to the repair of other tissue types, we believe we are making unique contributions to stem cell biology and regenerative medicine.

Profesor and Research Director Maimónides University, Buenos Aires · CIITT

I am a physician graduated from the Faculty of Medicine of the National University of La Plata, Argentina (1976). I had a fellowship of seven years with the National Council of Scientific Research and Technology (CONICET) where I obtained my postgraduate training in cell biology. I were professor in different universities: Univ. de La Plata, Univ. Nacional de Cuyo, Wayne State University (Detroit, USA) and Morehause University (Atlanta, USA). Between 1993 and 1995 I developed the tumor cell- activated B cell hybrid (TBH) vaccine. The safety and efficiency results of this vaccine were presented in the European Society of Haemapheresis (Vienna, 1995) and published in Transfusion Science in 1997 (17: 643-649). In 2000, I presented to the American Society for Aphaeresis the Dendritic Cell vaccine boosted with the TBH vaccine.

The Institute of Mother and Child in Warsaw, Poland
Provisional title: Efficacy and safety of the use of autologic adipose derived regenerative cells (ADRC) in pediatric patients with an autoimmune determined refractory epilepsy.

Associate professor of Pediatric Neurology, general neurologist, epileptologist
Professional affiliation:
Head of Clinic of Neurology of Children and Adolescents,
Institute of Mother and Child in Warsaw, Poland
Member of The Scientific Board of the Institute of Mother and Child Member of the Managing Board of the Polish Society of Child Neurologists
Member of Polish Society of Epileptologii Vice-President of Warsaw Division of the Polish Society of Child Neurologists
Lecturer of Medical Centre for Postgraduate Education in Warsaw.

Ludwik Hirszfeld Institute of Immunology and Experimental Therapy, the Polish Academy of Sciences
Neurosurgery Clinic, Medical University in Wroclaw

H-index 13
2004 Ph.D. in medicine: The role of prolin rich protein from ovine colostrum on maturation of immature human thymocytes, Wrocław Medical University
1989-1995 Wrocław Medical University, Faculty of Medicine

Stanford Burnham Medical Research Institute, California

Professor and Director of the Program in Development & Regenrative Cell Biology (the Stem Cell Program) at the Burnham Institute, coordinator of the Southern California Stem Cell Consortium, a faculty member in the Department of Pediatrics, and Director of the Basic Science Program in Neonatology at the University of California, San Diego. His research focuses on stem cell biology (including human), neurobiology, animal models of disease states, and transplantation. Dr. Snyder is also board certified in pediatrics, neurology (with special competence in children), and neonatology (newborn intensive care) having completed his clinical post-graduate training at Harvard Medical School and Children's Hospital-Boston. He continues to be clinically active in all these disciplines. He received PhD in neurobiology at the University of Pennsylvania and completed a postdoctoral fellowship in the Dept. of Genetics at Harvard Medical School.

Mossakowski Medical Research Centre, Polish Academy of Sciences
Neurologist and Neurobiologist; Head of Translational Platform for Regenerative Medicine ( TRM Platform); secretary of  Polish Society of Neurology, Warsaw Branch; secretary of  Cell Therapy Team of The Central Nervous System Diseases and the council member of International Association of Neurorestoratology

STUDIED on Warsaw Medical University

from 1966 employed in Mossakowski’s Medical Research Center (MMRC) of Polish Academy of Sciences (PAS).
1986- 1996 Associated Professor in Department of Neurochemistry,
1996- 2000 Chief of Molecular Neuropathology Unit
2000- 2011 Organizer and Director of NeuroRepair Department in MMRC.